Medical breakthrough: Japanese researchers explore rectal oxygenation method with potential to revolutionize lung disease treatment
Recent studies by Japanese scientists from Osaka University are opening new horizons in medical technology, particularly in the treatment of lung diseases.
They are developing an innovative method of supplemental oxygenation by delivering oxygen-rich fluid rectally, which does not absorb into the bloodstream but enriches the body with oxygen.
This idea is not entirely new; in 2024, scientists tested it on laboratory animals such as pigs, mice, and rats, earning a prestigious Ig Nobel Prize.
According to researcher Takanori Takebe, this method could reduce dependence on bulky and expensive ventilators, making oxygen therapy more accessible and easier to administer.
The initial clinical trials on humans confirmed that the technique is safe and well-tolerated, marking a significant step toward widespread adoption.
Participants received perfluorodecalin—a special liquid capable of binding 40-50 times more oxygen than water and twice as much as human blood—administered through a enema and held for an hour.
Importantly, no serious side effects were observed, although some participants reported mild discomfort and bloating.
Beyond its medical implications, the research also explores the potential extraction of fluorine from recycled Teflon cookware, which could have industrial significance.
Experts believe this technology could replace or supplement existing oxygenation systems, significantly reducing costs and increasing accessibility especially in emergency situations or for chronic respiratory conditions like pneumonia or lung cancer.
Takanori Takebe continues to impress the medical community with innovative ideas and breakthroughs in regenerative medicine and organoid technologies, opening new avenues for science and healthcare.